The Ramblings of a Middle Aged Fertility Physician whose life revolves around Eggs, Sperms & Embryos....
Tuesday, September 22, 2009
Alaska
Tom had been in the liquor business for 25 years. Finally, sick of the stress, he quits his job and buys 50 acres of land in Alaska, as far from humanity as possible.He sees the postman once a week and gets groceries once a month. Otherwise it's total peace and quiet.After six months or so of almost total isolation, someone knocks on his door. He opens it, and a huge, bearded man is standing there.
"Name's Lars, your neighbour from forty miles up the road. Having a Christmas party Friday night... Thought you might like to come. About 5:00."
"Great", says Tom, "after six months out here I'm ready to meet some local folks. Thank you."
As Lars is leaving, he stops. "Gotta warn you......be some drinking'"...
"Not a problem" says Tom. "After 25 years in the business, I can drink with the best of 'em."
Again, the big man starts to leave and stops. "More 'n' likely gonna be some fighting' too"...
"Well, I get along with people, I'll be all right. I'll be there, Thanks again."
"More'n likely be some wild sex, too"...
"Now that's really not a problem," says Tom, warming to the idea. "I've been all alone for six months! I'll definitely be there. By the way, what should I wear?"
"Don't much matter .... Just gonna be the two of us"...
Monday, September 21, 2009
HOW DO YOU DECIDE WHO TO MARRY? (written by kids)
(1) You got to find somebody who likes the same stuff. Like, if you like sports, she should like it that you like sports, and she should keep the chips and dip coming.
- Alan, age 10
(2) No person really decides before they grow up who they're going to marry. God decides it all way before, and you get to find out later who you're stuck with.
- Kristen, age 10
WHAT IS THE RIGHT AGE TO GET MARRIED?
(1) Twenty-three is the best age because you know the person FOREVER by then.
- Camille, age 10
(2) No age is good to get married at. You got to be a fool to get married.
- Freddie, age 6
(very wise for his age)
HOW CAN A STRANGER TELL IF TWO PEOPLE ARE MARRIED?
(1) You might have to guess, based on whether they seem to be yelling at the same kids.
- Derrick, age 8
WHAT DO YOU THINK YOUR MOM AND DAD HAVE IN COMMON?
(1) Both don't want any more kids.
- Lori, age 8
WHAT DO MOST PEOPLE DO ON A DATE?
(1) Dates are for having fun, and people should use them to get to know
each other. Even boys have something to say if you listen long enough.
- Lynnette, age 8
(isn't she a treasure)
(2) On the first date, they just tell each other lies and that Usually gets them interested enough to go for a second date.
- Martin, age 10
(Who said boys do not have brains)
WHAT WOULD YOU DO ON A FIRST DATE THAT WAS TURNING SOUR?
(1) I'd run home and play dead. The next day I would call all the newspapers and make sure they wrote about me in all the dead columns.
-Craig, age 9
WHEN IS IT OKAY TO KISS SOMEONE?
(1) When they're rich.
- Pam, age 7
(I could not have said it better myself)
(2) The law says you have to be eighteen, so I wouldn't want to mess with that.
- Curt, age 7
(Good Point)
(3 )The rule goes like this: If you kiss someone, then you should marry them and have kids with them. It's the right thing to do.
- Howard, age 8
(Who made the rule)
IS IT BETTER TO BE SINGLE OR MARRIED?
It's better for girls to be single but not for boys. Boys need someone to clean up after them.
- Anita, age 9
(bless you child)
HOW WOULD THE WORLD BE DIFFERENT IF PEOPLE DIDN'T GET MARRIED?
(1 ) There sure would be a lot of kids to explain, wouldn't there?
- Kelvin, age 8
And the #1 Favourite is........
HOW WOULD YOU MAKE A MARRIAGE WORK?
(1 ) Tell your wife that she looks pretty, even if she looks like a truck.
- Ricky, age 10
( The boy already understands)
- Alan, age 10
(2) No person really decides before they grow up who they're going to marry. God decides it all way before, and you get to find out later who you're stuck with.
- Kristen, age 10
WHAT IS THE RIGHT AGE TO GET MARRIED?
(1) Twenty-three is the best age because you know the person FOREVER by then.
- Camille, age 10
(2) No age is good to get married at. You got to be a fool to get married.
- Freddie, age 6
(very wise for his age)
HOW CAN A STRANGER TELL IF TWO PEOPLE ARE MARRIED?
(1) You might have to guess, based on whether they seem to be yelling at the same kids.
- Derrick, age 8
WHAT DO YOU THINK YOUR MOM AND DAD HAVE IN COMMON?
(1) Both don't want any more kids.
- Lori, age 8
WHAT DO MOST PEOPLE DO ON A DATE?
(1) Dates are for having fun, and people should use them to get to know
each other. Even boys have something to say if you listen long enough.
- Lynnette, age 8
(isn't she a treasure)
(2) On the first date, they just tell each other lies and that Usually gets them interested enough to go for a second date.
- Martin, age 10
(Who said boys do not have brains)
WHAT WOULD YOU DO ON A FIRST DATE THAT WAS TURNING SOUR?
(1) I'd run home and play dead. The next day I would call all the newspapers and make sure they wrote about me in all the dead columns.
-Craig, age 9
WHEN IS IT OKAY TO KISS SOMEONE?
(1) When they're rich.
- Pam, age 7
(I could not have said it better myself)
(2) The law says you have to be eighteen, so I wouldn't want to mess with that.
- Curt, age 7
(Good Point)
(3 )The rule goes like this: If you kiss someone, then you should marry them and have kids with them. It's the right thing to do.
- Howard, age 8
(Who made the rule)
IS IT BETTER TO BE SINGLE OR MARRIED?
It's better for girls to be single but not for boys. Boys need someone to clean up after them.
- Anita, age 9
(bless you child)
HOW WOULD THE WORLD BE DIFFERENT IF PEOPLE DIDN'T GET MARRIED?
(1 ) There sure would be a lot of kids to explain, wouldn't there?
- Kelvin, age 8
And the #1 Favourite is........
HOW WOULD YOU MAKE A MARRIAGE WORK?
(1 ) Tell your wife that she looks pretty, even if she looks like a truck.
- Ricky, age 10
( The boy already understands)
Sunday, September 20, 2009
US company offers celebrity ‘look-a-like’ sperm
A California-based fertility company is offering prospective parents a range of celebrity 'look-a-like' sperm donors. Cryobank, which is also planning to offer services in New York, allows customers to search through a database according to characteristics such as ethinicity and eye colour without revealing donors' photographs. In addition, the company has now added features that resemble celebrities such as David Beckham and David Blaine.
Cryobank's introduction on its website reads: ‘Have you ever wondered if your favorite donor looks like anyone famous? You know how tall he is and his hair and eye color, but wouldn't it be great to have an idea of what he really LOOKS like? Now you can find out with a click of your mouse!'
Scott Browne, a spokesman for Cryobank said that 'the intention is not to suggest the child will look like one of the celebrities. It's just to personalise the donor. I think in their heads they know the medical history is most important, but ultimately we're all interested in what someone looks like. It's what we do when we're dating or meet someone. I didn't ask my wife her medical history before I decided to marry her.'
Potential sperm donors are put through a rigorous screening process delving into their health and medical history before finding out which celebrity they most closely resemble. Browne says the process of deciding which donor resembles which celebrity is not easy: 'There's a lot that goes into it. It's not just sitting in a room deciding who looks like Ben Affleck, what sounded really easy got complicated when we realised that people see people in completely different ways,' he said. He added: 'So we're very concerned about misleading clients. One rule we made was that a donor never gets just one celeb. And one of our representatives can always get on the phone and explain.'
The company's New York Park Avenue branch will not be open for a few months but from this week prospective parents can search the database online for celebrity look-a-like sperm.
Cryobank's introduction on its website reads: ‘Have you ever wondered if your favorite donor looks like anyone famous? You know how tall he is and his hair and eye color, but wouldn't it be great to have an idea of what he really LOOKS like? Now you can find out with a click of your mouse!'
Scott Browne, a spokesman for Cryobank said that 'the intention is not to suggest the child will look like one of the celebrities. It's just to personalise the donor. I think in their heads they know the medical history is most important, but ultimately we're all interested in what someone looks like. It's what we do when we're dating or meet someone. I didn't ask my wife her medical history before I decided to marry her.'
Potential sperm donors are put through a rigorous screening process delving into their health and medical history before finding out which celebrity they most closely resemble. Browne says the process of deciding which donor resembles which celebrity is not easy: 'There's a lot that goes into it. It's not just sitting in a room deciding who looks like Ben Affleck, what sounded really easy got complicated when we realised that people see people in completely different ways,' he said. He added: 'So we're very concerned about misleading clients. One rule we made was that a donor never gets just one celeb. And one of our representatives can always get on the phone and explain.'
The company's New York Park Avenue branch will not be open for a few months but from this week prospective parents can search the database online for celebrity look-a-like sperm.
Saturday, September 19, 2009
Friday, September 18, 2009
Thursday, September 17, 2009
Baby Oliver is now a Beacon of Hope for IVF patients
A British woman has become the first in the world to give birth using a new IVF test that promises to improve the chances of parenthood for infertile couples.
A boy, named Oliver, was born in July to a 41-year-old woman who had tried 13 cycles of IVF without success. She conceived after her eggs were screened to select those that were the most viable.
The screening technique has the potential to raise IVF success rates significantly, particularly for women in their late 30s and 40s and couples with a history of failed fertility treatment or miscarriage. It could also be used in younger women to promote the use of a single embryo in IVF to guard against risky multiple births. If the test can pick the best eggs, one embryo could be transferred to the womb without reducing success rates.
Simon Fishel, managing director of the CARE Fertility Group in Nottingham, who treated the new parents, said: “Oliver’s birth is an important landmark in shaping our understanding of why many women fail to become pregnant.”
He said that older versions of the screening test have been shown to double the chances of IVF success for some couples with a poor prognosis, and that early results suggest that the new technique is at least as good, if not better.
Since the pregnancy that led to Oliver’s birth was announced in January, about five more women have conceived after taking the egg test, known as Array Comparative Genomic Hybridisation (Array CGH), out of about 20 treated.
All the patients treated had a poor prognosis, with multiple failed attempts at IVF, and Dr Fishel said that the early success rate of about 25 per cent was a considerable improvement. “I’d generally give these women about a 10 per cent chance of getting pregnant,” he said.
The effectiveness of Array CGH, however, has yet to be assessed in a randomised controlled trial — the gold standard for medical therapies — and other scientists were more cautious about its prospects. Several other quality tests for eggs and embryos have looked promising at first, but have been found wanting by randomised trials.
Tony Rutherford, chairman of the British Fertility Society, welcomed the birth, but added: “It is absolutely essential that these new techniques are subject to further rigorous research; and should only be offered to patients within the context of a robustly designed clinical trial, carried out in suitably experienced centres.
"The widespread use of this technology should await the outcome of such research to ensure we know which patients might benefit. All too often we see ground-breaking news about techniques that seem to offer great hope, but fail to live up to expectations when applied in widespread clinical practice.”
Array CGH seeks to identify eggs that have the wrong number of chromosomes, which will generally fail to develop properly if fertilised with sperm. Such chromosomal abnormalities are difficult to detect in eggs or embryos by eye, and they are among the major causes of IVF failure.
Array CGH has two main advantages over other methods of screening: the first is “gene chip” technology that tests DNA very quickly, so that eggs or embryos do not need to be frozen while they are checked. The second is that instead of removing cells from embryos, which can damage them, it relies on testing the eggs, which are the cause of 85 per cent of chromosomal defects.
Healthy human cells have 46 chromosomes, 23 inherited from each parent. Before an egg is fertilised, it ejects half of its complement to leave space for the 23 paternal chromosomes carried by the sperm. The waste chromosomes are jettisoned in a structure called the polar body and are a mirror image of those left behind in the egg.
Array CGH checks that an egg’s polar body has 23 chromosomes: if it does not, its parent egg must have too many or too few. Doctors can then ensure that only normal eggs are fertilised to produce viable embryos for transfer to the womb.
Oliver’s mother produced eight eggs, of which only two were found to be normal and transferred to the womb. In several other cases Dr Fishel’s team has found no eggs suitable for transfer.
The test costs £1,950, on top of the £3,000 or so for IVF. It is not available on the NHS or at other private clinics.
Professor Peter Braude, of King’s College London, said: “I am delighted that this patient has achieved her positive outcome after so many years of trying. However we need to be cautious as to whether the new technique was responsible.
“I hope that this is not the case here and would love to see a positive outcome to rigorous analysis of this technique, but at the moment this can only be viewed as a potentially very lucky result.”
Wednesday, September 16, 2009
Senior Citizens
Next time you use a pair of rubber gloves, you're going to smile when you think of this:
A dentist noticed that his next patient, a little old lady, was nervous, so he decided to tell her a little joke as he put on his gloves.
'Do you know how they make these gloves?' he asked.
'No, I don't,' she replied.
'Well,' he spoofed, 'there's a building in Canada with a big tank of latex, and workers of all hand sizes walk up to the tank, dip in their hands, let them dry,
then peel off the gloves and throw them into boxes of the right size.'
She didn't crack a smile.
'Oh, well. I tried,' he thought.
But five minutes later, during a delicate portion of the procedure, she burst out laughing.
'What's so funny?' he asked.
'I was just envisioning how condoms are made!'
(Gotta watch those little old ladies! Their minds are always working!)
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