The Ramblings of a Middle Aged Fertility Physician whose life revolves around Eggs, Sperms & Embryos....
Wednesday, September 1, 2010
Pair guilty over illegal internet sperm company
Two men have been found guilty of illegally making sperm available over the internet.
Ricky Gage, 49, and Nigel Woodforth, 43, from Reading, operated Fertility 1st which made sperm available from anonymous donors without a licence.
The men had denied three counts of procuring sperm illegally under the Human Fertilisation and Embryology Act.
They were granted conditional bail but the judge warned them she was considering a prison sentence and fine.
The men will be sentenced at Southwark Crown Court on 24 September.
At the start of the trial the pair had argued that their company was simply an information site which acted as an introduction database, meaning they were not procuring or making sperm available.
But jurors heard a list showed 792 deliveries had been made by the company, which helped make the men an estimated income of £250,000 between October 2007 and November 2008.
It is the first time anyone has been prosecuted under the Human Fertilisation and Embryology Act 1990.
Long waiting lists, shortages of sperm and restrictions on who can obtain treatment may be some of the reasons why women have opted to use unlicensed fertility clinics, also the impression that it might be easier to seek treatment online.
But anyone using fresh sperm from an unlicensed clinic is taking a potentially serious risk because they cannot be sure of the quality of the donation or whether it is free of sexually transmitted diseases.
At licensed clinics donors are given a blood test on the day of donation, repeated six months later because HIV can take this long to show up.
Sperm is frozen during this quarantine period and is only made available once the screening has been done and it has been checked for quality.
The men were reported to the Human Fertilisation and Embryology Authority (HFEA) after one of their clients complained about their unprofessional standards.
Melissa Bhalla-Pentley was hoping to have a baby with her partner when she ordered the sperm through the Fertility 1st website set up by Gage and Woodforth.
Ms Bhalla-Pentley paid the men £380 in total and another £150 for courier delivery and the sperm donor's expenses.
However, she contacted the company when a copy of the donor's medical tests was sent to her with his name visible.
Under the HFEA's Act, the firm should have had a licence.
The law was brought in to ensure that both donors and women wanting to conceive had access to information and counselling, and to help protect against the risks of diseases including HIV.
The website run by Gage and Woodforth, which promised women a "life-changing opportunity towards motherhood", boasted of having more than 300 donors nationwide and a 37% success rate.
Clients were allowed to choose the ethnicity, height, hair colour, education and even hobbies of the sperm donor.
Following the verdict, Professor Lisa Jardine, chair of the HFEA, said: "Getting access to fertility services can be difficult and there can be some very strong emotional pressures when trying to start a family.
"But unlicensed internet sites like these are exploiting women.
"This is a victory for those women."
Tuesday, August 31, 2010
‘Fast frozen’ sperm increases IVF hope
Their sperm could benefit from a rapid-freezing process which preserves up to 80 per cent of sperm activity for IVF treatment, compared with up to 40 per cent using existing slow-freezing techniques.
The new vitrification method – which sees sperm plunged into liquid nitrogen – sees seminal plasma removed, meaning HIV and other viruses can be taken out, say experts from Chile and Germany.
Vitrification is already used to quick-freeze eggs and embryos successfully for IVF treatment.
The findings were ‘very exciting’, said Ian Cooke, professor emeritus at Sheffield University.
‘In addition, the prospect of use with HIV positive patients has great potential, although we’d want to confirm the absence of residual HIV in sperm samples.’
The new vitrification method – which sees sperm plunged into liquid nitrogen – sees seminal plasma removed, meaning HIV and other viruses can be taken out, say experts from Chile and Germany.
Vitrification is already used to quick-freeze eggs and embryos successfully for IVF treatment.
The findings were ‘very exciting’, said Ian Cooke, professor emeritus at Sheffield University.
‘In addition, the prospect of use with HIV positive patients has great potential, although we’d want to confirm the absence of residual HIV in sperm samples.’
Monday, August 30, 2010
Team Uncovers Possible Risk Gene For Schizophrenia
An international team of researchers has identified a risk gene for schizophrenia, including a potentially causative mutation, using genome-wide association data-mining techniques and independent replications.
The results of the research, led by Xiangning Chen, Ph.D., associate professor of psychiatry and human and molecular genetics in Virginia Commonwealth University's School of Medicine and the Virginia Institute for Psychiatric and Behavioral Genetics, and Kenneth S. Kendler, M.D., professor of psychiatry and human and molecular genetics in VCU's School of Medicine and the Virginia Institute for Psychiatric and Behavioral Genetics, are reported in the September issue of the journal Molecular Psychiatry.
In recent years, scientists have used genome-wide association studies to identify possible candidate genes responsible for diseases that include type 2 diabetes, lung cancer, Parkinson's disease, rheumatoid arthritis and systemic lupus erythematosus. However, the same approach was not as successful for the study of schizophrenia.
According to Chen, one of the many possible reasons is that many genes are involved in schizophrenia and the effect of each individual gene is relatively small. For this reason, he said, results obtained from individual samples tend to fluctuate.
Chen said that to obtain consistent results researchers need to consider the results from many independent samples. The team used that approach in this study by first screening two genome-wide association datasets with statistic, genomic, informatic and genetic data and then ranking the top candidate. Chen said that the selected candidates were verified by more than 20 independent samples.
According to Chen, the work is one of the largest genetic studies of schizophrenia and included more than 33,000 participants that identify cardiomyopathy associated 5, or CMYA5, as a risk gene for schizophrenia. Its function is unknown at this time.
"While its implication for patient care is not clear at this moment, it is fair to say that our paper provides a new target for future research and a practical method to identify other potential risk genes. The findings are one of the most consistent findings in recent literature," said Chen.
The study was supported in part by the Stanley Medical Research Institute, the National Alliance for Research on Schizophrenia and Depression and the National Institute of Mental Health. Part of the genotyping was funded by the Genetic Association Information Network organization and Eli Lilly and Company.
The results of the research, led by Xiangning Chen, Ph.D., associate professor of psychiatry and human and molecular genetics in Virginia Commonwealth University's School of Medicine and the Virginia Institute for Psychiatric and Behavioral Genetics, and Kenneth S. Kendler, M.D., professor of psychiatry and human and molecular genetics in VCU's School of Medicine and the Virginia Institute for Psychiatric and Behavioral Genetics, are reported in the September issue of the journal Molecular Psychiatry.
In recent years, scientists have used genome-wide association studies to identify possible candidate genes responsible for diseases that include type 2 diabetes, lung cancer, Parkinson's disease, rheumatoid arthritis and systemic lupus erythematosus. However, the same approach was not as successful for the study of schizophrenia.
According to Chen, one of the many possible reasons is that many genes are involved in schizophrenia and the effect of each individual gene is relatively small. For this reason, he said, results obtained from individual samples tend to fluctuate.
Chen said that to obtain consistent results researchers need to consider the results from many independent samples. The team used that approach in this study by first screening two genome-wide association datasets with statistic, genomic, informatic and genetic data and then ranking the top candidate. Chen said that the selected candidates were verified by more than 20 independent samples.
According to Chen, the work is one of the largest genetic studies of schizophrenia and included more than 33,000 participants that identify cardiomyopathy associated 5, or CMYA5, as a risk gene for schizophrenia. Its function is unknown at this time.
"While its implication for patient care is not clear at this moment, it is fair to say that our paper provides a new target for future research and a practical method to identify other potential risk genes. The findings are one of the most consistent findings in recent literature," said Chen.
The study was supported in part by the Stanley Medical Research Institute, the National Alliance for Research on Schizophrenia and Depression and the National Institute of Mental Health. Part of the genotyping was funded by the Genetic Association Information Network organization and Eli Lilly and Company.
Sunday, August 29, 2010
Fertility scientists find way of 'restarting' ovaries
Women who go through early menopause and are unable to have children have been given fresh hope after scientists found a way of "restarting" ovaries.
The study could pave the way for women to one day conceive even though they have gone through the menopause at an early age.
Premature ovarian failure affects 1% of women under 40, and one in 1,000 (0.1%) under 30. The normal age for menopause is debatable but experts consider early menopause as before 45.
Possible reasons include chromosome abnormalities, such as Down's syndrome; enzyme deficiencies, which can damage eggs and prevent the production of the hormone oestrogen; and autoimmune diseases, where the body effectively turns on itself.
Scientists at the World Congress of Fertility and Sterility in Munich said the latest work on rats could offer hope for the future.
A team from Cairo University used stem cells to restore ovarian function in a group of 60 female rats. The rats were divided into four groups, with the first not given any treatment and acting as a control.
Rats in all the other groups were treated with a chemical to stop their ovaries working, with those in the second group then given injections containing stem cells.
Group three was injected with a saline solution to act as a control, and the group four rats had ovarian failure but received no treatment, also enabling them to act as a control.
The Cairo team tested the hormone levels of all the rats to see if they returned to normal following treatment.
Within two weeks, the rats in group two, which had been treated with stem cells, had regained full ovarian function.
After eight weeks, their hormone levels were the same as rats who did not have ovarian failure.
Male stem cells were used so researchers could confirm their presence in the ovaries of the treated group by searching for the Y chromosome.
Professor Osama Azmy, who led the study, said: "The treated ovaries returned to producing eggs and hormones, and we could detect the presence of the stem cells within the newly functioning ovaries.
"What we have done is proven that we can restore apparently fully functioning ovaries in rats. The next step is to look how these rats might reproduce, and to characterise the chromosomes of offspring following treatment.
"We have not yet reached the stage of producing offspring, and so we will need to understand if the baby rats will be genetically related to the mother, or to the donor of the stem cells.
"This is proof of concept and there is still a long way to go before we can apply this to women.
"Nevertheless, this work holds out the possibility that women with premature ovarian failure might be able to bear a baby of their own."
Saturday, August 28, 2010
Friday, August 27, 2010
Thursday, August 26, 2010
Camphor- The effective & healthy mosquito repellent
Malaria and Dengue are on a steep rise in major Metros in India. We all must be using liquid or the old blue tablet type of mosquito repellents sold under various names. Despite their use, it is common to see mosquitoes hovering around with the best of repellents in action. Secondly, we cannot use these mosquito repellents whole day – be they be of any brand. Thirdly, many people land up with allergies due to them.
In the past, man would light diyas and burn camphor on a regular basis as a part of daily puja. These helped to purify the air and keep harmful bacteria, viruses and mosquitoes away! We can definitely have a better and healthy environment with the use of camphor.
Camphor or Kapur is a waxy, white or transparent substance extracted from the wood of the Camphor Laurel tree found in Asia. Camphor has many known medicinal uses-It relieves nasal congestion and cough when rubbed on the chest as an oil. Camphor is used as an ingredient in throat lozenges and cough syrups and in Vicks. Camphor is also used in some anti-itch ointments, creams and cooling gels because it is can be absorbed through skin and is effective at treating pain locally. It has an analgesic effect which makes it a favorite oil to be used in pain relieving massage blends for sore muscles and arthritic pain. Camphor is known to improve the quality of air making it a better for our lungs and heart.
Many people are not aware of the Mosquito repellent power of Camphor - a simple solution without side effects and very cost effective. CAMPHOR IS A NATURAL MOSQUITO REPELLENT With effect round the clock! You do not need to burn it for that. There are three easier ways to do it:
1. Put 2 tablets of commercially available camphor on any warm surface- the device shown in the picture serves the purpose well. Plug it for an hour and see the results! You can do it twice a day- morning and in the night as well!
2. Place 2 tablets of camphor on different corners of the room or at places where mosquitoes seem to love to stay! Leave them there and they will evaporate in a day or so keeping the air purer and mosquito free.
3. Take a wide opened cup or plate with water. Drop 2 tablets of Camphor into the water. Keep the cup with water and camphor in your sleeping room. The quantity of water and camphor may differ from room size. Water evaporate at normal temperature. Camphor slowly started dissolving in water. The water evaporates with Camphor smell. Adding little bit hot water gives instant action.
You will be amazed at the results! Do experience it and help spread these healthy tips!
In the past, man would light diyas and burn camphor on a regular basis as a part of daily puja. These helped to purify the air and keep harmful bacteria, viruses and mosquitoes away! We can definitely have a better and healthy environment with the use of camphor.
Camphor or Kapur is a waxy, white or transparent substance extracted from the wood of the Camphor Laurel tree found in Asia. Camphor has many known medicinal uses-It relieves nasal congestion and cough when rubbed on the chest as an oil. Camphor is used as an ingredient in throat lozenges and cough syrups and in Vicks. Camphor is also used in some anti-itch ointments, creams and cooling gels because it is can be absorbed through skin and is effective at treating pain locally. It has an analgesic effect which makes it a favorite oil to be used in pain relieving massage blends for sore muscles and arthritic pain. Camphor is known to improve the quality of air making it a better for our lungs and heart.
Many people are not aware of the Mosquito repellent power of Camphor - a simple solution without side effects and very cost effective. CAMPHOR IS A NATURAL MOSQUITO REPELLENT With effect round the clock! You do not need to burn it for that. There are three easier ways to do it:
1. Put 2 tablets of commercially available camphor on any warm surface- the device shown in the picture serves the purpose well. Plug it for an hour and see the results! You can do it twice a day- morning and in the night as well!
2. Place 2 tablets of camphor on different corners of the room or at places where mosquitoes seem to love to stay! Leave them there and they will evaporate in a day or so keeping the air purer and mosquito free.
3. Take a wide opened cup or plate with water. Drop 2 tablets of Camphor into the water. Keep the cup with water and camphor in your sleeping room. The quantity of water and camphor may differ from room size. Water evaporate at normal temperature. Camphor slowly started dissolving in water. The water evaporates with Camphor smell. Adding little bit hot water gives instant action.
You will be amazed at the results! Do experience it and help spread these healthy tips!
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