Device offers cheaper IVF during lunch break

A new approach to fertility treatment that could allow women to have a cheaper form of IVF in their lunch hour is being developed. The Invocell device is designed to enable IVF to be performed without complex laboratory equipment and could make the procedure faster, more convenient and less expensive.

In standard IVF, eggs are fertilised with sperm outside the body, and any resulting embryos are left to develop in culture for three to five days before the best are transferred to the womb. The Invocell device is a sealed capsule that allows fertilisation to take place inside the body, in the vaginal cavity.

A woman would first be given mild drugs to stimulate her ovaries, and then eggs would be removed from them while she was under sedation. Up to seven eggs would then be put into the Invocell capsule, along with washed sperm.The capsule would then be placed inside the vagina. After three days, the patient would return for a second appointment, during which the capsule would be removed and any fertilised embryos examined for quality. The best one or two eggs would be transferred to thewomb.

The first appointment would take about 90 minutes and the second half an hour, according to Claude Ranoux, of BioXcell, the Massachusetts-based company that developed the device. Because eggs, sperm and embryos would at no point be stored outside the body, the technique means IVF could be performed in a doctor's office, without incurring the costs involved in incubation. Dr Ranoux said this would cut the cost of fertility treatment by hundreds of pounds. The typical bill in Britain is about Sterling pounds 2500 ($5300) a cycle.

BioXcell has completed about 800 trial cycles, obtaining a clinical pregnancy rate of 19.7per cent. The average success rate for conventional treatments for women aged under 35 in Britain is 29.6 per cent. BioXcell has applied for approval for the device from the US Food and Drug Administration, and it has also received a European Union CE mark.

Dr Ranoux said the company hoped to market it in Europe, including Britain, later this year.

Disfigured Wounded US Soldiers To Get New Skin, Ears & Fingers

The US Department of Defense has announced a five year program to develop new stem-cell based treatments for service members disfigured from war-time injuries. The new Armed Forces Institute of Regenerative Medicine (AFIRM) will explore the use of a patient's own stem cells to grow replacement skin, tissue and other body parts. AFIRM will collaborate with the US Army Institute of Surgical Research, in San Antonio, Texas and several universities including Wake Forest University, North Carolina; Rutgers University in New Jersey; and the University of Pittsburgh in Pennsylvania.
The new initiative aims to use stem cell technology to make new skin, tendons, muscles, as well as new body parts such as ears, fingers and noses. Speaking at a press conference held last week, Lt Gen Eric Schoomaker cited the case of a badly-burned Marine, who will receive a new nose and ears grown using his own stem cells. He added 'the cells that we're talking about actually exist in our bodies today'.
The use of improvised explosive devices (IEDs) in Iraq and Afghanistan is apparently the main reason for a marked increase in severe blast trauma, which now accounts for three quarters of all injuries. Within five years, AFIRM hope to develop new therapies for burn repair, wound healing without scarring, facial reconstruction and limb reconstruction or regeneration. 'We're embarking on a new generation of research that's going to redefine the Army and military medicine as we know it today', said Schoomaker.
Dr Anthony Atala, director of the Institute for Regenerative Medicine at Wake Forest University, explained: 'All the parts of your body, tissues and organs, have a natural repository of cells that are ready to replicate when an injury occurs'. The scientists hope to harness this regenerative ability to grow replacement tissue that will not be rejected by the patient's body. For replacement body parts such as ears, the cells will be 'painted' on to a biodegradable scaffold, and incubated for a few weeks before being transplanted on to the patient's body. AFIRM will receive around $250 million over the initial five years,
about $80 million of which will come from the Department of Defense, with the remaining funding coming from other private and public organisations, including the National Institutes of Health.

Little wonder from India

A teenager from India who stands at a tiny 1ft 11in (58cm) tall is the smallest girl in the world. Jyoti Amge, 14, is shorter than the average two-year-old child and only weighs 11lb (5kg). Jyoti is smaller than the average two-year-old child. She has a form of dwarfism called achondroplasia and won't grow any taller than her current height. Due to her size, Jyoti has to have clothes and jewellery made for her. She sleeps in a tiny bed and uses special plates and cutlery to eat, as normal-sized utensils are too big. Despite this, she goes to a regular school in Nagpur, central India, where she has her own small desk and chair, and her classmates treat her like any other student.
Jyoti also shares common interests with other teenagers, with a love for DVDs and fashionable dresses. She said: 'I am proud of being small. I love all the attention I get. I'm not scared of being small and I don't regret it. 'I'm just the same as other people. I eat like you, dream like you. I don't feel any different.' Jyoti is treated like a mini-celebrity in her home town, where people flock to meet her and some even treat her like a goddess. She will even be releasing an album with her favourite Indian pop star, the bhangra/rap star Mika Singh.
Her mum, Ranjana Amge, 45, said: 'When Jyoti was born, she seemed quite normal. We came to know about her disorder when she was five. 'We consulted a specialist and he said she will be this size all of her life. Jyoti is small, yet cute, and we love her very much.' Jyoti is ambitious and hopes to work as a Bollywood actress one day. She said: 'I would love to work in a big city like Mumbai, act in films and travel to London and America.
Jyoti chats to her friends on her phone, just like any other teenager . 'I'm proud of being small. I love all the attention I get because of it.' Her dad, Kishanji Amge, 52, said: 'I can't separate myself from her even for a single day. I love her very much.
'She makes me proud. Lots of gurus come to see and bless her. They pray for her happiness and long life.'

Salaam Bombay!

-Churchgate has neither a church nor a gate. It is a railway station.
-There is no darkness in Andheri.
-Lalbaag is neither red nor a garden.
-No King ever stayed at King's Circle .
-Nor did Queen Victoria stay at Victoria Terminus.
-Nor is there any Princess at Princess Street .
-Lower Parel is at the same level as Parel
-There are no marines or sailors at Marine Lines.
-The Mahalaxmi temple is at Haji Ali not at Mahalaxmi.
-There are no pigs traded at Dukkar bazaar.
-Teen batti is a junction of 3 roads, not three lamps.
-Trams used to terminate at Kings circle not Dadar* Tram Terminus (Dadar TT.).
-Breach Candy is not a sweetmeat market, but famous for a Hospital.
-Safed Pool has the dirtiest and blackest water.
-You cannot buy coal at Kolsa street.
-There are no Iron smiths at Lohar chawl.
-There are no pot makers at Kumbhar wada.
-Lokhandwala complex is not an Iron and steel market.
-Null bazaar does not sell taps.
-You will not find ladyfingers at Bhendi Bazaar.
-Kalachowki does not have a black Police station.
-Hanging Gardens are not suspended.
-Mirchi Gully does not sell chillies.
-Figs do not grow in Anjir Wadi.
-Sitafals do not grow in Sitafal Wadi,
-Jackfruits do not grow at Fanaswadi.
-But it is true that you may get fleeced at Chor Bazaar!
-AMCHI MUMBAI
-A City where everything is possible, especially the impossible .

-Where telephone bills make a person ill,
-Where a person cannot sleep without a pill.
-Where carbon-dioxide is more than oxygen,
-Where the road is considered to be a dustbin,
-Where college canteens are full and classes empty,
-Where Adam teasing is also making an entry,
-Where a cycle reaches faster than a car,
-Where everyone thinks himself to be a star,
-Where sky scrapers overlook the slum,
-Where houses collapse as the monsoon comes,
-Where people first act and then think,
-Where there is more water in the pen than ink,
-Where the roads see-saw in monsoon,
-Where the beggars become rich soon,
-Where the roads are leveled when the minister arrives,
-Where college admission means hard cash,
-Where cement is frequently mixed with ash.
-This is Mumbai my dear, But don't fear, just cheer, come to Mumbai every year!

THINGS TO PROVE YOU'RE A BOMBAYITE
1. You say 'town ' and expect everyone to know that this means south of Churchgate.
2 You speak in a dialect of Hindi called 'Bambaiya Hindi', which only Bombayites can understand.
3. Your door has more than three locks.
4. Rs 500 worth of groceries fit in one paper bag.
5. Train timings ( 9.27 , 10.49 etc) are really important events of life.
6. You spend more time each month traveling than you spend at home.
7. You call an 8' x 10' clustered room a Hall.
8.. You're paying Rs 10,000,00 for a 1 room flat, the size of walk-in closet and you think it's a 'steal.'
9. You have the following sets of friend: school friends, college friends, neighborhood friends, office friends and yes, train friends, a species unique only in Bombay. (REALLY TRUE!)
10. Cabbies and bus conductors think you are from Mars if you call the roads by their Indian name, they are more familiar with Warden Road, Peddar Road, Altamount Road ....
11. Stock market quotes are the only other thing* besides cricket which you follow passionately.
12. The first thing that you read in the Times of India is the 'Bombay Times' supplement.
13. You take fashion seriously.
14.You're suspicious of strangers who are actually nice to you-Hookers, beggars and the homeless are invisible.
16. You compare Bombay to New York 's Manhattan instead of any other cities of India.
16. The most frequently used part of your car is the horn.
17. You insist on calling CST as VT, and Sahar and Santacruz airports instead of Chatrapati Shivaji International Airport.
18. You consider eye contact an act of overt aggression.
19. Your idea of personal space is no one actually standing on your toes.
20. Being truly alone makes you nervous.
21. You love wading through knee deep mucky water in the monsoons, and actually call it ''romantic'.
22. Only in Bombay, you would get Chinese Dosa and Jain Chicken

Salaam Bombay!!

-Anonymous Mumbaite

Breaking News

Click http://www.rbmonline.com/Article/3145 to go straight to the abstract. Rotunda has just published its latest work in RBM online!
Cheers!!

Weight Watcher

Blond Genes

A blonde, wanting to earn some extra money, decided to hire herself out as a "handywoman" and started canvassing a nearby well-to-do neighborhood.


She went to the front door of the first house, and asked the owner if he had any odd jobs for her to do.


"Well, I guess I could use somebody to paint my porch," he said, "How much will you charge me?"


The blonde quickly responded, "How about $50?"

The man agreed and told her that the paint and everything she would
need was in the garage.

The man's wife, hearing the conversation, said to her husband, "Does she realize that our porch goes all the way around the house?"


He responded, "That's a bit cynical, isn't it?"

The wife replied, "You're right. I guess I'm starting to believe all
those 'dumb blonde' jokes we've been getting by e-mail lately."

A short time later, the blonde came to the door to collect her money.


"You're finished already?" the husband asked.

"Yes," the blonde replied, "and I had paint leftover, so I gave it two coats."


Impressed, the man reached into his pocket for the $50 and handed it
to her.

"And by the way," the blonde added, "it's not a Porch, it's a Lexus".