Despite IVF being used for thirty years, fertility treatments are still breaking new ground to assist couples struggling to conceive children - in multiples. Recently the first US babies conceived using frozen eggs were born in Minnesota and now quadruplets have been born in California to two mothers within a same-sex partnership.
After two unsuccessful IVF cycles and a miscarriage, Ceresa and Jonathan Caudill succeeded in having the first babies in Minnesota to be born from frozen eggs rather than embryos. In California, partners Karen Wesolowski, 42, and Martha Padgett, 38, underwent fertility treatments for between three and four years, spending roughly INR 29,75,000 on five cycles of IVF, before having the first reported quadruplets to ever be born two mothers when they each had twins using IVF embryos created from Padgett’s eggs and a sperm donor.
The egg-freezing technology which successfully led to the birth of the Caudill’s twin daughters is an imperfect science. The egg is the body’s largest cell and, unlike sperm and embryos, is predominantly composed of water which crystallises during the freezing process and can damage it. Experts hope that, once reliable, the technique could significantly help women to control their reproductive destinies. Researchers posture that the technology could impact reproductive choice in much the same way that the birth control pill did forty years ago. ‘For women who are sure they are going to go through menopause from cancer treatments, or for women in their mid-30s who don't see a partner on the horizon, there really aren't other options’, said Dr. Elizabeth Ginsberg, president-elect of the Society for Assisted Reproductive Technology (SART) and a fertility doctor in Boston.
According to Dr. Charles Coddington who heads the Mayo fertility clinic in Rochester, many couples like the Caudills do not wish to create more embryos than are required for implantation because they are uncomfortable with concept of unused leftover embryos. The Caudills used the remaining eggs, which had been frozen for research purposes, as a last resort.
The Mayo Clinic now offers egg-freezing to women, including those who wish to delay pregnancy, for double the price of frozen-embryo storage - at roughly INR 42,500 - and makes it clear that the success rates is much lower to conceive children using this method. Only half of frozen eggs survive the thawing process compared to the Mayo Clinic’s 90 per cent survival rate for embryos. Then 10-15 per cent of those thawed eggs successfully lead to live births where as frozen embryos have a 50 per cent chance of leading to a live birth at the clinic. They use a technique that removes much of the water in the eggs before slowly freezing them and later thaw them slowly returning the water to the eggs for re-absorption.
The California couple had attempted every possible IVF combination, using both of their eggs, and was ‘exhausted’. After five unsuccessful attempts they were just trying to hedge their bets to successfully have a single child but were delighted to learn that they were each pregnant and that they were both having twins. The two sets of twins were surprisingly born only 22 hours apart. The couple is ‘thrilled, knowing they’re all related and can help each other through life’.
The Ramblings of a Middle Aged Fertility Physician whose life revolves around Eggs, Sperms & Embryos....
Tuesday, August 5, 2008
Monday, August 4, 2008
Doubts…
1. When dog food is new and improved tasting, who tests it?
2. If the 'black box' flight recorder is never damaged during a plane crash, why isn't the whole airplane made out of that stuff?
3. Who copyrighted the copyright symbol?
4. Can you cry under water?
5. Why do people say, 'You've been working like a dog' when dogs just sit around all day?
6. Why are the numbers on a calculator and a phone reversed?
7. Do fish ever get thirsty?
8. Can you get cornered in a round room?
9. Why do birds not fall out of trees when they sleep?
10. If corn oil is made from corn, and vegetable oil is made from vegetables then what is baby oil made from?
11. What should one call a male ladybird?
12. If a person suffered from amnesia and then was cured would they remember that they forgot?
13. Can you blow a balloon up under water?
14. Why is it called a 'building' when it is already built?
15. If you were traveling at the speed of sound and you turned on your radio would you be able to hear it?
16. If you're traveling at the speed of light and you turn your headlights on, what happens?
17. Why is it called a TV set when there's only one?
18. Why do most cars have speedometers that go up to at least 200 when you legally can't go that fast on any road?
2. If the 'black box' flight recorder is never damaged during a plane crash, why isn't the whole airplane made out of that stuff?
3. Who copyrighted the copyright symbol?
4. Can you cry under water?
5. Why do people say, 'You've been working like a dog' when dogs just sit around all day?
6. Why are the numbers on a calculator and a phone reversed?
7. Do fish ever get thirsty?
8. Can you get cornered in a round room?
9. Why do birds not fall out of trees when they sleep?
10. If corn oil is made from corn, and vegetable oil is made from vegetables then what is baby oil made from?
11. What should one call a male ladybird?
12. If a person suffered from amnesia and then was cured would they remember that they forgot?
13. Can you blow a balloon up under water?
14. Why is it called a 'building' when it is already built?
15. If you were traveling at the speed of sound and you turned on your radio would you be able to hear it?
16. If you're traveling at the speed of light and you turn your headlights on, what happens?
17. Why is it called a TV set when there's only one?
18. Why do most cars have speedometers that go up to at least 200 when you legally can't go that fast on any road?
Sunday, August 3, 2008
Saturday, August 2, 2008
Tonight We Have The Stars at LaVaSa
Do not worry if you have built your castles in the air. They are where they should be. Now put the foundations under them.
-Henry David Thoreau
I came. I saw. I was mesmerized. I decided to settle down. I made my retirement plans. I made my castles in the air. I leased out my future home from Lavasa Corporation. I will now utilize the rest of my life in putting the foundations to my dreams at Lavasa. With a playground that covers the whole valley, outdoors that start right at your doorstep, chances are you will run out of excuses to live life at Lavasa. Nature trails that zigzag across the hills, offer a perfect recreational activity for nature lovers. Parks at Lavasa offer countless relaxation and leisure activities for its residents. For those of you following my Lavasa Life, let me today write about the night-life at Lavasa.
How good is the night sky over your house? How well can you see the stars? How many stars can you see from your house? If you really want to see the beauty of the night sky, drive down to Lavasa. Many factors determine how well you can see the night sky. Natural weather patterns have an obvious effect. But even when clouds are not seen, high haze, which may well be invisible to you, can obscure many stars. Humidity causes air to scatter light, reducing the contrast between the "black” sky and the stars, making fainter stars harder to see and stars close together difficult to distinguish. What you might see as three stars on a clear, dark night may look like only one with high levels of humidity in the air. But by far the biggest thief of the night sky is light pollution. Light pollution won't cause physical or mental health problems. It won't give you cancer, but it is a cancer on the beauty of the night sky. It robs us of a natural treasure. City-folks, you don't know what you are missing. I did not too till I saw the night sky at Lavasa. It was one of those rare clear-sky nights during the monsoons at Lavasa (I think the most beautiful season of the year at Lavasa).
The International Dark-Sky Association ( www.darksky.org) defines light pollution as "any adverse effect of manmade light. It is often used to denote urban sky glow.” The association describes several types of light pollution, including glare, light trespass and energy waste. All forms of light pollution deal with light going to places where it is not needed or wanted. Some forms of light pollution, while intended to make you safer at night, actually do more harm than good. Environmental sensitivity is one of the driving factors in the development of Lavasa. Modern technologies merged with time tested ideas have been deployed to maintain the natural settings of the environment. The Environment Management Plan (EMP) addresses several initiatives to protect and enhance the green cover. As far as I know, only 12% of the total area of 25,000 hectares will be developed. The remainder will be left as it is. Presently Ekaant -the Lodge is the only tourist recreational facility at Dasve. You see small clusters of lights at night from Ekaant in villages comprising of 15-20 tenements. The only other lights seen in the valley are the street lamps over the road made on the Warasgaon Dam.
The long, warm nights of August provide some dazzling sights. The Milky Way arcs high overhead, adding a soft glow to the dark sky -- but only if you are away from pesky city lights. The constellations Sagittarius and Scorpius are at their best, anchoring the southern end of the Milky Way. Jupiter points the way to Sagittarius. Mars and Saturn drop from sight in the glare of sunset, where Venus and Mercury already lurk. That leaves Jupiter as the only naked-eye planet easily visible for most of the month. if you have a telescope, this is the place to see the stars at night, especially on a warm dry night at Lavasa.
The lights bring out the character of Ekaant. Strong, Silent, Handsome & Eternal. Look at the pictures. I fell in love all over again, once again:) with the stars & the night-lights of Lavasa. I had some friends writing to me from Israel asking if they can buy a retreat at Lavasa. Must remember to forward their enquiries to Nathan & colleagues. I wish these visionaries had started this project in the 70s. Anyways my children and their children will enjoy the fruits of people who are shaping the future modern India.
The greatest use of life is to spend it for something that will outlast it.
-William James
Doctors Never Laugh
...the Doctor replied 'Of course I won't laugh, I'm a professional. In
over twenty years I've never laughed at a patient.'
'Okay then,' Bob said, and proceeded to drop his trousers, revealing the
tiniest 'whoo-ha' the doctor had ever seen.
It couldn't have been bigger than the size of a AAA battery.
Unable to control himself, the doctor started giggling, then fell laughing
to the floor. Ten minutes later he was able to struggle to his feet and
regain his composure.
'I'm so sorry,' said the doctor. 'I really am. I don't know what came over
me. On my honor as a doctor and a gentleman, I promise it won't happen
again. Now, what seems to be the problem?'
'It's swollen,' Bob replied.
over twenty years I've never laughed at a patient.'
'Okay then,' Bob said, and proceeded to drop his trousers, revealing the
tiniest 'whoo-ha' the doctor had ever seen.
It couldn't have been bigger than the size of a AAA battery.
Unable to control himself, the doctor started giggling, then fell laughing
to the floor. Ten minutes later he was able to struggle to his feet and
regain his composure.
'I'm so sorry,' said the doctor. 'I really am. I don't know what came over
me. On my honor as a doctor and a gentleman, I promise it won't happen
again. Now, what seems to be the problem?'
'It's swollen,' Bob replied.
Friday, August 1, 2008
Thursday, July 31, 2008
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