The Ramblings of a Middle Aged Fertility Physician whose life revolves around Eggs, Sperms & Embryos....
Friday, April 4, 2008
Rusty Genes
After their baby was born, the panicked father went to see the Obstetrician. 'Doctor,' the man said, 'I don't mind telling you, but I'm a little upset because my daughter has red hair.
She can't possibly be mine.' 'Nonsense,' the doctor said. 'Even though you and your wife both have black hair, one of your ancestors may have contributed red hair to the gene pool.'
'It isn't possible,' the man insisted. 'This can't be, our families on both sides had jet-black hair for generations.'
'Well,' said the doctor, 'let me ask you this. How often do you have sex?' The man seemed a bit ashamed.
'I've been working very hard for the past year. We only made love once or twice every few months.'
'Well, there you have it!' The doctor said confidently. 'It's rust.'
Thursday, April 3, 2008
Uk creates the First Hybrid Embryos
Scientists at Newcastle University have created part-human, part-animal hybrid embryos for the first time in the UK, the BBC revealed today. The embryos survived for up to three days and are part of medical research into a range of illnesses. It comes a month before MPs are to debate the future of such research. The Catholic Church describes it as "monstrous". But medical bodies and patient groups say such research is vital for our understanding of disease. They argue that the work could pave the way for new treatments for conditions such as Parkinson's and Alzheimer's. These hybrid embryos were created by injecting DNA derived from human skin cells into eggs taken from cows ovaries which have had virtually all their genetic material removed. The Newcastle team say they are using cow ovaries because human eggs from donors are a precious resource and in short supply. The hybrid embryos are purely for research and would never be allowed to develop beyond 14 days when they are still smaller than a pinhead. Scientists want to extract stem cells, the body's master cells, from the embryos, in order to increase understanding of a whole range of diseases from diabetes to stroke and ultimately to produce treatments.
Professor John Burn from Newcastle University says the research is entirely ethical. "This is licensed work which has been carefully evaluated. This is a process in a dish, and we are dealing with a clump of cells which would never go on to develop. It's a laboratory process and these embryos would never be implanted into anyone. "We now have preliminary data which looks promising but this is very much work in progress and the next step is to get the embryos to survive to around six days when we can hopefully derive stem cells from them." The research in Newcastle was approved by the UK's fertility regulator, the Human Fertilisation and Embryology Authority. It acted ahead of the passing of new legislation which will specifically allow the creation of hybrid embryos so as not to hold back research.
Critics from the Roman Catholic Church say the creation of hybrids is immoral. "It is difficult to imagine a single piece of legislation which more comprehensively attacks the sanctity and dignity of human life than this particular bill," Cardinal Keith O'Brien, archbishop of St Andrews and Edinburgh declared last week. Dr David King, of Human Genetics Alert, said: "For anyone who understands basic biology, it is no surprise that these embryos died at such an early stage. "Cloning is inefficient precisely because it is so unnatural, and by mixing species it becomes even more unnatural and unlikely to succeed. "The public has been grossly misled by the hype that this is vital medical research. "Even if stem cells were ever to be produced, like cloned animals, they would have so many errors of their metabolism that they would produce completely misleading data."
Not for the first time developments in science have outpaced the debate from legislators. For supporters of embryo research the creation of hybrid embryos is a small but significant move forward. For opponents it is a step too far.
Wednesday, April 2, 2008
Labor of Love
To our neighbors, my wife, Nancy, and I don't appear in the least unusual. To those in the quiet Oregon community where we live, we are viewed just as we are -- a happy couple deeply in love. Our desire to work hard, buy our first home, and start a
family was nothing out of the ordinary. That is, until we decided that I would carry our child.
I am transgender, legally male, and legally married to Nancy. Unlike those in same-sex marriages, domestic partnerships, or civil unions, Nancy and I are afforded the more than 1,100 federal rights of marriage. Sterilization is not a requirement for sex
reassignment, so I decided to have chest reconstruction and testosterone therapy but kept my reproductive rights. Wanting to have a biological child is neither a male nor female desire, but a human desire.
Ten years ago, when Nancy and I became a couple, the idea of us having a child was more dream than plan. I always wanted to have children. However, due to severe endometriosis 20 years ago, Nancy had to undergo a hysterectomy and is unable to
carry a child. But after the success of our custom screen-printing business and a move from Hawaii to the Pacific Northwest two years ago, the timing finally seemed right. I stopped taking my bimonthly testosterone injections. It had been roughly
eight years since I had my last menstrual cycle, so this wasn't a decision that I took lightly. My body regulated itself after about four months, and I didn't have to take any exogenous estrogen, progesterone, or fertility drugs to aid my pregnancy.
Our situation sparks legal, political, and social unknowns. We have only begun experiencing opposition from people who are upset by our situation. Doctors have discriminated against us, turning us away due to their religious beliefs. Health care
professionals have refused to call me by a male pronoun or recognize Nancy as my wife. Receptionists have laughed at us. Friends and family have been unsupportive; most of Nancy's family doesn't even know I'm transgender. This whole process, from trying to get pregnant to being pregnant, has been a challenge for us. The first doctor we approached was a reproductive endocrinologist.
He was shocked by our situation and told me to shave my facial hair. After a $300 consultation, he reluctantly performed my initial checkups. He then required us to see the clinic's psychologist to see if we were fit to bring a child into this world and
consulted with the ethics board of his hospital. A few months and a couple thousand dollars later, he told us that he would no longer treat us, saying he and his staff felt uncomfortable working with "someone like me." In total, nine different doctors have been involved. This is why it took over one year to get access to a cryogenic sperm bank to purchase anonymous donor vials, and why Nancy and I eventually resorted to home insemination. When I finally got pregnant for the first time, I ended up having an ectopic pregnancy with triplets. It was a life-threatening event that required surgical intervention, resulting in the loss of all embryos and my right fallopian tube. When my brother found out about my loss, he said, "It's a good thing that happened. Who knows what kind of monster it would have been."
On successfully getting pregnant a second time, we are proud to announce that this pregnancy is free of complications and our baby girl has a clean bill of health. We are happily awaiting her birth, with an estimated due date of July 3, 2008. How does it feel to be a pregnant man? Incredible. Despite the fact that my belly is growing with a new life inside me, I am stable and confident being the man that I am. In a technical sense I see myself as my own surrogate, though my gender identity as male is constant. To Nancy, I am her husband carrying our child -- I am so lucky to have such a loving, supportive wife. I will be my daughter's father, and Nancy will be her mother. We will be a family. Outside the local medical community, people don't know I'm five months' pregnant. But our situation ultimately will ask everyone to embrace the gamut of human possibility and to define for themselves what is normal.
By Thomas Beatie
View this story online at: http://www.alternet.org/story/80450/
family was nothing out of the ordinary. That is, until we decided that I would carry our child.
I am transgender, legally male, and legally married to Nancy. Unlike those in same-sex marriages, domestic partnerships, or civil unions, Nancy and I are afforded the more than 1,100 federal rights of marriage. Sterilization is not a requirement for sex
reassignment, so I decided to have chest reconstruction and testosterone therapy but kept my reproductive rights. Wanting to have a biological child is neither a male nor female desire, but a human desire.
Ten years ago, when Nancy and I became a couple, the idea of us having a child was more dream than plan. I always wanted to have children. However, due to severe endometriosis 20 years ago, Nancy had to undergo a hysterectomy and is unable to
carry a child. But after the success of our custom screen-printing business and a move from Hawaii to the Pacific Northwest two years ago, the timing finally seemed right. I stopped taking my bimonthly testosterone injections. It had been roughly
eight years since I had my last menstrual cycle, so this wasn't a decision that I took lightly. My body regulated itself after about four months, and I didn't have to take any exogenous estrogen, progesterone, or fertility drugs to aid my pregnancy.
Our situation sparks legal, political, and social unknowns. We have only begun experiencing opposition from people who are upset by our situation. Doctors have discriminated against us, turning us away due to their religious beliefs. Health care
professionals have refused to call me by a male pronoun or recognize Nancy as my wife. Receptionists have laughed at us. Friends and family have been unsupportive; most of Nancy's family doesn't even know I'm transgender. This whole process, from trying to get pregnant to being pregnant, has been a challenge for us. The first doctor we approached was a reproductive endocrinologist.
He was shocked by our situation and told me to shave my facial hair. After a $300 consultation, he reluctantly performed my initial checkups. He then required us to see the clinic's psychologist to see if we were fit to bring a child into this world and
consulted with the ethics board of his hospital. A few months and a couple thousand dollars later, he told us that he would no longer treat us, saying he and his staff felt uncomfortable working with "someone like me." In total, nine different doctors have been involved. This is why it took over one year to get access to a cryogenic sperm bank to purchase anonymous donor vials, and why Nancy and I eventually resorted to home insemination. When I finally got pregnant for the first time, I ended up having an ectopic pregnancy with triplets. It was a life-threatening event that required surgical intervention, resulting in the loss of all embryos and my right fallopian tube. When my brother found out about my loss, he said, "It's a good thing that happened. Who knows what kind of monster it would have been."
On successfully getting pregnant a second time, we are proud to announce that this pregnancy is free of complications and our baby girl has a clean bill of health. We are happily awaiting her birth, with an estimated due date of July 3, 2008. How does it feel to be a pregnant man? Incredible. Despite the fact that my belly is growing with a new life inside me, I am stable and confident being the man that I am. In a technical sense I see myself as my own surrogate, though my gender identity as male is constant. To Nancy, I am her husband carrying our child -- I am so lucky to have such a loving, supportive wife. I will be my daughter's father, and Nancy will be her mother. We will be a family. Outside the local medical community, people don't know I'm five months' pregnant. But our situation ultimately will ask everyone to embrace the gamut of human possibility and to define for themselves what is normal.
By Thomas Beatie
View this story online at: http://www.alternet.org/story/80450/
Tuesday, April 1, 2008
Captain Hook
A seaman meets a pirate in a bar, and they take turns telling their adventures on the seas. The seaman notes that the pirate has a wooden leg, a hook on the end of his arm, and an eye patch.
The seaman asks "So, how did you end up with the wooden leg?"
The pirate replies "We were in a storm at sea, and I was swept overboard into a school of sharks. Just as my men were pulling me out of the sea, a shark bit off my leg."
"Wow!" said the seaman. "What about your hook"?
"Well.....", replied the pirate, "We were boarding an enemy ship and were battling the other sailors with swords. One of the enemy cut off my hand."
"Incredible!" remarked the seaman. "How did you get the eye patch"?
"A seagull dropping fell into my eye.", replied the pirate.
"You lost your eye to a seagull dropping?" the sailor asked incredulously.
"Well.....", said the pirate, ".....it was my first day with the hook............"
Monday, March 31, 2008
Cancer scan reveals surprise for mum, 57
A 57-year-old woman has become one of the oldest first time mothers in the UK, after initially being told that her pregnancy could be ovarian cancer. Eight weeks prior to giving birth, Susan Tollefsen was sent for emergency hospital tests on a growing swelling, suspected to be ovarian cancer, only to be told by the sonographer that she was 30 weeks pregnant. Ms Tollefsen, a teacher, and her partner Nick Mayer, had been attempting to conceive for several years, but in the UK IVF is not funded for women over 40. The couple had travelled to a Moscow clinic to have fertility treatment using donor eggs, which had been fertilised with Mr Mayer's sperm. In August last year Ms Tollefsen was taken to hospital having suffered a suspected miscarriage, which appeared to be confirmed by blood tests. A later examination revealed an abdominal mass, which then turned out to be the pregnancy. Ms Tollefsen believes that she miscarried one of her twins, and that the other one survived.
Nine weeks after the scan revealed the pregnancy, Ms Tollefsen's daughter Freya was born by caesarean section, weighing 6lb 6oz. Ms Tollefsen said, 'the doctor held her up, I took one look and burst into tears'. Medical checks confirmed that Freya was healthy and had developed normally.
In 2006, 62-year old Patricia Rashbrook became the UK's oldest woman to have a child, following treatment with donor eggs carried out in Eastern Europe. The oldest woman in the world to have given birth following fertility treatment is Adriana Iliescu, a Romanian woman, who gave birth aged 66 in 2005. Clinics in the UK are not likely to treat women in their fifties and sixties - even though it is not illegal to do so, most clinics have an upper age limit and few would treat women over the age of 45.
Nine weeks after the scan revealed the pregnancy, Ms Tollefsen's daughter Freya was born by caesarean section, weighing 6lb 6oz. Ms Tollefsen said, 'the doctor held her up, I took one look and burst into tears'. Medical checks confirmed that Freya was healthy and had developed normally.
In 2006, 62-year old Patricia Rashbrook became the UK's oldest woman to have a child, following treatment with donor eggs carried out in Eastern Europe. The oldest woman in the world to have given birth following fertility treatment is Adriana Iliescu, a Romanian woman, who gave birth aged 66 in 2005. Clinics in the UK are not likely to treat women in their fifties and sixties - even though it is not illegal to do so, most clinics have an upper age limit and few would treat women over the age of 45.
Sunday, March 30, 2008
Saturday, March 29, 2008
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